Ethelsville is a town in Pickens County, Alabama, United States. As of the 2010 census, the population of the town was 81, unchanged from 2000. The town was named after Ethel Hancock, a one time resident and staple of the community. It was incorporated in 1952.Ethelsville is located at 33°24′49″N 88°12′56″W / 33.41361°N 88.21556°W / 33.41361; -88.21556.According to the U.S. Census Bureau, the town has a total area of 0.6 square miles, all land.As of the 2010 United States Census, there were 81 people residing in the town. 74.1% were White and 25.9% were African American.As of the census of 2000, there were 81 people, 37 households, and 23 families residing in the town. The population density was 143.2 people per square mile. There were 43 housing units at an average density of 76.0 per square mile. The racial makeup of the town was 86.42% White and 13.58% Black or African American.There were 37 households out of which 21.6% had children under the age of 18 living with them, 45.